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More grist for the mill. Here is a Bloomberg story..... BusinessWeek Logo
Monday May 3, 2010
Bloomberg
Growth Hormone Makes Sprinters Faster in First Athlete Study
May 03, 2010, 9:03 PM EDT
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By Jason Gale
May 4 (Bloomberg) -- Growth hormone injected daily for eight weeks may cut 0.4 of a second off a sprinter's time over 100 meters, according to the first study to measure the effect on athletes of a drug used to boost competitiveness.
Athletes taking human growth hormone, or hGH, improved sprint capacity by 4 percent to 5 percent, researchers at the Garvan Institute in Sydney found. The World Anti-Doping Agency funded the study, which appeared yesterday in the Annals of Internal Medicine.
The finding gives the first scientific evidence supporting the agency's ban on hGH, which can cause deformities and increase the risk of heart disease. The performance-enhancing effect of hGH -- produced in the pituitary gland and given to children with a height-restricting deficiency -- is limited to sprinting and almost doubles in men when combined with testosterone, the authors said.
"We found the enhancement in sprint capacity would correlate to a 0.4 second improvement over 10 seconds in a 100- meter dash,"Â said Ken Ho, Garvan's head of pituitary research and a co-author of the study, in a statement. "This improvement could turn the last-place finisher in the Olympic finals into a gold medal winner."Â
Jamaica's Usain Bolt won the 100-meter sprint at the 2008 Beijing Olympics in a world-record breaking time of 9.69 seconds. Darvis Patton of the U.S. finished last with a time of 10.03 seconds.
Novo Nordisk
More than 100 recreational athletes ages 18 to 40 were recruited in the Garvan study. Participants were randomly selected to receive a daily shot of recombinant hGH made by Bagsvaerd, Denmark-based Novo Nordisk A/S or a saline placebo. A subset of the 68 men enrolled in the study also received a weekly testosterone injection.
The growth-hormone doses were below what athletes are reported to use, and for a shorter time, the researchers said. The anti-doping agency prohibits the use of growth hormone by competitive athletes.
"The drug's effects on performance might be greater than shown in this study, and its side effects might be more serious,"Â Ho said.
An excess of growth hormone may lead to a syndrome known as acromegaly that can cause disfigurement of the face, enlargement of the heart and joints, and premature death. Long-term hGH abuse may also cause diabetes, Ho said in a telephone interview.
Physical performance over a series of endurance and power exercises was analyzed for each participant before and at the completion of an eight-week regimen, and six weeks post- treatment. Hormone levels, body composition and adverse reactions were also recorded.
Swelling and Pain
Growth hormone didn't improve recipients' strength, power or endurance, nor increase muscle mass, the researchers found. The improvement in sprint performance wasn't observed six weeks after treatment ceased and was associated with body fluid retention, swelling and joint pain.
"It's a really exciting finding,"Â Ho said in the interview. "It justifies the banning of growth hormone."Â
A blood test for hGH was introduced at the 2004 Olympics in Athens and English rugby league player Terry Newton became the first athlete sanctioned for its use last February.
--Editors: Phil Serafino, Kristen Hallam
To contact the reporter on this story: Jason Gale at j.gale@bloomberg.net
To contact the editor responsible for this story: Reg Gale at rgale5@bloomberg.net
Monday May 3, 2010
Bloomberg
Growth Hormone Makes Sprinters Faster in First Athlete Study
May 03, 2010, 9:03 PM EDT
More From Businessweek
Story Tools
* e-mail this story
* print this story
* digg this
* save to del.icio.us
* add to Business Exchange
By Jason Gale
May 4 (Bloomberg) -- Growth hormone injected daily for eight weeks may cut 0.4 of a second off a sprinter's time over 100 meters, according to the first study to measure the effect on athletes of a drug used to boost competitiveness.
Athletes taking human growth hormone, or hGH, improved sprint capacity by 4 percent to 5 percent, researchers at the Garvan Institute in Sydney found. The World Anti-Doping Agency funded the study, which appeared yesterday in the Annals of Internal Medicine.
The finding gives the first scientific evidence supporting the agency's ban on hGH, which can cause deformities and increase the risk of heart disease. The performance-enhancing effect of hGH -- produced in the pituitary gland and given to children with a height-restricting deficiency -- is limited to sprinting and almost doubles in men when combined with testosterone, the authors said.
"We found the enhancement in sprint capacity would correlate to a 0.4 second improvement over 10 seconds in a 100- meter dash,"Â said Ken Ho, Garvan's head of pituitary research and a co-author of the study, in a statement. "This improvement could turn the last-place finisher in the Olympic finals into a gold medal winner."Â
Jamaica's Usain Bolt won the 100-meter sprint at the 2008 Beijing Olympics in a world-record breaking time of 9.69 seconds. Darvis Patton of the U.S. finished last with a time of 10.03 seconds.
Novo Nordisk
More than 100 recreational athletes ages 18 to 40 were recruited in the Garvan study. Participants were randomly selected to receive a daily shot of recombinant hGH made by Bagsvaerd, Denmark-based Novo Nordisk A/S or a saline placebo. A subset of the 68 men enrolled in the study also received a weekly testosterone injection.
The growth-hormone doses were below what athletes are reported to use, and for a shorter time, the researchers said. The anti-doping agency prohibits the use of growth hormone by competitive athletes.
"The drug's effects on performance might be greater than shown in this study, and its side effects might be more serious,"Â Ho said.
An excess of growth hormone may lead to a syndrome known as acromegaly that can cause disfigurement of the face, enlargement of the heart and joints, and premature death. Long-term hGH abuse may also cause diabetes, Ho said in a telephone interview.
Physical performance over a series of endurance and power exercises was analyzed for each participant before and at the completion of an eight-week regimen, and six weeks post- treatment. Hormone levels, body composition and adverse reactions were also recorded.
Swelling and Pain
Growth hormone didn't improve recipients' strength, power or endurance, nor increase muscle mass, the researchers found. The improvement in sprint performance wasn't observed six weeks after treatment ceased and was associated with body fluid retention, swelling and joint pain.
"It's a really exciting finding,"Â Ho said in the interview. "It justifies the banning of growth hormone."Â
A blood test for hGH was introduced at the 2004 Olympics in Athens and English rugby league player Terry Newton became the first athlete sanctioned for its use last February.
--Editors: Phil Serafino, Kristen Hallam
To contact the reporter on this story: Jason Gale at j.gale@bloomberg.net
To contact the editor responsible for this story: Reg Gale at rgale5@bloomberg.net