I think he's "queer" because he gets into these catty little arguments with Hillary Clinton ("She talks about gun control like she's Annie Oakley -- shame on her!") which to me seems effeminate and also damaging to the credibility of his party; also, he manipulates racial politics to suit his own needs rather than serve the greater good of the country.
I think he'll get shot at often as president because a lot of people will find him unacceptable and far too emotionally drive -- aka girlish -- to be the commander of the free world.
Not to say anyone will actually succeed in getting to him -- a lot of attempts have probably also been made on GWB -- just that they'll try.